Thermo Fisher Scientific Human BANF1 Synthetic Peptide
인간 BANF1 단백질의 N-말단 19개 아미노산 서열에 해당하는 합성 펩타이드. PA5-20329 항체의 블로킹 펩타이드로 사용 가능. 염색체 단백질 BANF1 연구용으로 적합. PBS(pH 7.2)와 0.1% BSA 포함, -20°C 보관.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the amino terminus of human BANF1.
PEP-0449 can be used as a blocking peptide with polyclonal antibody PA5-20329.
Target Information
Barrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double-stranded DNA. BANF1 also interacts with a family of nuclear proteins that include LAP2, emerin, and MAN1. It is a host cell component of retroviral pre-integration complexes (PICs), including those of HIV. BANF1 binds to p55 Gag (the structural precursor of HIV-1 virions) as well as its cleaved product matrix. In addition to being a host cell component of the PIC, BANF1 is thought to be present at low levels in incoming virions and may contribute to the assembly or activity of HIV-1 PICs through direct binding to matrix and DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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