Thermo Fisher Scientific ABCG5 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.1–0.5 µg/mL

Product Specifications

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes.
ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This protein is a member of the White subfamily and functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols.
It is expressed in a tissue-specific manner in the liver, colon, and intestine.
This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8.
Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일명: PA5-78702_ABCG5_Q9H222-1_Rabbit.svg, PA5-78702_ABCG5_Q9H222-1_Rabbit_PDP.jpeg)