Thermo Fisher Scientific PIGF Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 PIGF 단백질 검출용 Rabbit Polyclonal Antibody. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS buffer에 보관하며, 4°C 단기 및 -20°C 장기 보관 권장.
- 카탈로그번호
- PA575899
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human PIGF |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.3 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2719627 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Phosphatidylinositol-glycans (PIGs) are multi-pass transmembrane proteins localized in the endoplasmic reticulum. They are essential for the biosynthesis of glycosylphosphatidylinositol (GPI) anchors. Some PIG proteins are part of the GPI transamidase complex, recognizing either the GPI attachment signal or the lipid portion of GPI. Others function as glycosyltransferases, transferring N-acetylglucosamine (GlcNAc) to phosphatidylinositol (PI).
PIG-F acts as an auxiliary subunit of ethanolamine phosphate (EtNP) transferases, associating with PIG-O for expression and stability. Together, they catalyze the transfer of EtNP to the third mannose (Man-3) of GPI. Mutations in the PIG-F gene can disrupt this process, leading to the absence of GPI-anchored proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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