Thermo Fisher Scientific HTR2B Polyclonal Antibody
인간 5-HT2B 수용체를 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. IHC(P)에서 1:100~1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 연구용으로만 사용.
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Thermo Fisher Scientific HTR2B Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the 2nd extracellular domain of human 5-HT2B Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2119731 |
Product Specific Information
PA1-20706 detects 5-HT2B Receptor in human samples.
Target Information
HTR2B is a G-protein coupled receptor for 5-hydroxytryptamine (serotonin). It functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformational change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors.
HTR2B also plays a role in perception of pain and regulation of behavior. It is required for normal proliferation of embryonic cardiac myocytes and normal heart development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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