Thermo Fisher Scientific ASIC4 Polyclonal Antibody
ASIC4 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, Flow cytometry 등 다양한 응용 가능. 인간, 생쥐, 랫드 반응성. 고순도 친화 크로마토그래피 정제. 연구용으로만 사용.
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Thermo Fisher Scientific ASIC4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:100–1:500 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human ASIC4 aa 250–450 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913407 |
Product Specific Information
- Positive Control: HepG2 cell lysate, human brain tissue lysate, K562 cell lysate, rat brain tissue, mouse pituitary tissue, SH-SY5Y
- Subcellular Location: Membrane
Target Information
ASIC4 belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels are involved in synaptic transmission, pain perception, and mechanoperception. The gene is predominantly expressed in the pituitary gland and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), though no correlation was found between mutations and PDC. Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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