Thermo Fisher Scientific VDR Monoclonal Antibody (517CT23.5.1)
VDR 단백질을 인식하는 Mouse IgA 단클론 항체로 Western blot에 최적화되어 있습니다. Human 시료에 반응하며, 비결합형 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgA |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 517CT23.5.1 |
| Immunogen | Purified His-tagged VDR protein (fragment) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897513 |
Target Information
Steroid receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone.
The 1,25-dihydroxy-vitamin D3 receptor (VDR) belongs to the superfamily of steroid hormone receptors, which includes estrogen, progesterone, glucocorticoid, androgen, and thyroid hormone receptors.
Vitamin D modulates calcium and phosphorus homeostasis, bone remodeling, cell growth regulation, and differentiation. VDR is found in the intestine, bone, kidney, epidermis, and endocrine immune system cells.
Repression of T-cell proliferation and IL-2 gene expression occurs when VDR binds within the IL-2 enhancer. Formation of VDR/retinoic X receptor (RXR) heterodimers in the presence of intracellular 1,25(OH)₂D₃ interferes with NFATp/Fos/Jun/DNA complex assembly and subsequent IL-2 transcription.
The corresponding gene for the vitamin D receptor is NR1I1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific Arylsulfatase A Monoclonal Antibody (498CT24.1.2)
656,000원
Thermo Fisher Scientific
Thermo Fisher Scientific GSTM1 Monoclonal Antibody (524CT17.2.5)
656,000원
Thermo Fisher Scientific
Thermo Fisher Scientific VDR Monoclonal Antibody (517CT23.5.1)
656,000원
Thermo Fisher Scientific
Thermo Fisher Scientific p57 Kip2 Monoclonal Antibody (522CT9.5.1)
656,000원
Thermo Fisher Scientific
Thermo Fisher Scientific BLNK Monoclonal Antibody (520CT6.1.1)
656,000원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|