Thermo Fisher Scientific EphB4 Polyclonal Antibody
Thermo Fisher Scientific의 EphB4 Polyclonal Antibody는 인간 및 마우스 시료에서 EPHB4 단백질을 검출하는 다클론 항체입니다. Western blot 및 IHC(P) 실험에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 PBS와 글리세롤 버퍼에 보관됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPHB4 (Accession P54760), corresponding to amino acid residues K960–Y987 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899826 |
Product Specific Information
Antibody detects endogenous levels of total EPHB4.
Target Information
EPHB4 is a receptor tyrosine kinase belonging to the ephrin receptor family. Members of the Eph family play important roles in biological processes such as nervous system development, angiogenesis, and synapse formation and maturation.
Ephrins are divided into two classes: ephrin-A (EFNA), anchored to the membrane by glycosylphosphatidylinositol linkage, and ephrin-B (EFNB), which are transmembrane proteins.
Eph receptors are grouped based on extracellular domain sequence similarity and ligand affinity. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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