Thermo Fisher Scientific EpoR Polyclonal Antibody
EpoR 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 시료에서 반응. Western blot 및 Immunocytochemistry에 적합하며, 고순도 Affinity chromatography로 정제됨. PBS와 50% glycerol 보존액, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPOR (Accession P19235), corresponding to amino acid residues S404–Y454 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899828 |
Product Specific Information
Antibody detects endogenous levels of total EPOR.
Target Information
EpoR encodes the erythropoietin receptor, a member of the cytokine receptor family. When erythropoietin binds to this receptor, it activates Jak2 tyrosine kinase and downstream pathways such as Ras/MAP kinase, PI3K, and STAT transcription factors. The activated receptor supports erythroid cell survival.
Defects in this gene may lead to erythroleukemia or familial erythrocytosis. Dysregulation may also influence tumor growth. Multiple transcript variants exist due to alternative splicing.
Diseases associated with EPOR include Erythrocytosis, Familial, 1 and Erythroleukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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