Thermo Fisher Scientific LPAR1 Monoclonal Antibody (OTI1G6), TrueMAB
Human LPAR1 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot, ICC/IF, Flow cytometry 등에 사용 가능. Lyophilized 형태로 제공되며, PBS 및 trehalose 완충액 포함. 연구용으로 세포 신호전달 및 성장 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G6 |
| Immunogen | Full length human recombinant protein of human LPAR1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, an additional desalting step is recommended (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
EDG2 (LPAR1) is a member of the G-protein coupled receptor family that binds lysophospholipids.
There are eight known members of the EDG receptor family, which are involved in regulating growth-related processes such as:
- Cellular proliferation
- Differentiation and survival
- Suppression of apoptosis
These receptors also mediate cytoskeleton-dependent effector functions including contraction, secretion, adhesion, and chemotaxis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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