Thermo Fisher Scientific HMOX1 Recombinant Rabbit Monoclonal Antibody (7H7W10)
HMOX1 단백질을 인식하는 토끼 단클론 항체로 Western blot, IHC, ICC, ELISA에 적합. 인간, 마우스, 랫트 반응성. 재조합 항체로 높은 특이성과 재현성 제공. -20°C 보관, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:800 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7H7W10 |
| Immunogen | Recombinant fusion protein containing amino acids 1–265 of human Heme Oxygenase 1 (HO-1/HMOX1) (NP_002124.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.52 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2849144 |
Product Specific Information
Immunogen sequence:
MERPQPDSMP QDLSEALKEA TKEVHTQAEN AEFMRNFQKG QVTRDGFKLV MASLYHIYVA LEEEIERNKE SPVFAPVYFP EELHRKAALE QDLAFWYGPR WQEVIPYTPA MQRYVKRLHE VGRTEPELLV AHAYTRYLGD LSGGQVLKKI AQKALDLPSS GEGLAFFTFP NIASATKFKQ LYRSRMNSLE MTPAVRQRVI EEAKTAFLLN IQLFEELQEL LTHDTKDQSP SRAPGLRQRA SNKVQDSAPV ETPRGKPPLN TRSQA
Target Information
Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to antioxidant molecules such as biliverdin and carbon monoxide. HO has two homologous isozymes: inducible HO-1 and constitutive HO-2. HO-1 is induced by oxidative stress, inflammatory agents, transforming growth factor beta, and heat shock. Increased HO-1 expression is believed to be a cellular defense mechanism against oxidative stress, as elevated HO can generate more bilirubin, a potent antioxidant.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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