Thermo Fisher Scientific Human Growth Hormone, Animal-Free Recombinant Protein, PeproTech
동물 성분이 없는 재조합 인간 성장호르몬 단백질로, 세포 증식 활성 검증 완료. 고순도(≥98%) 및 낮은 엔도톡신(<0.1 EU/µg)을 보장하며, 연구용으로 적합. E. coli 발현 시스템 기반, 건조 분말 형태로 공급.
- 카탈로그번호
- AF-100-40-250UG
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human Growth Hormone, Animal-Free Recombinant Protein, PeproTech
Applications
- Functional Assay (Functional): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | FPTIPLSRLF DNAMLRAHRL HQLAFDTYQE FEEAYIPKEQ KYSFLQNPQT SLCFSESIPT PSNREETQQK SNLELLRISL LLIQSWLEPV QFLRSVFANS LVYGASDSNV YDLLKDLEEG IQTLMGRLED GSPRTGQIFK QTYSKFDTNS HNDDALLKNY GLLYCFRKDM DKVETFLRIV QCRSVEGSCG F |
| Molecular Weight | 22.1 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | < 0.1 EU/µg |
| Activity | Stimulates proliferation of rat Nb2-11 cells. Expected ED50 ≤ 0.05 ng/ml; specific activity ≥ 2 × 10⁷ units/mg |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human Growth Hormone is a 22.1 kDa, single, non-glycosylated polypeptide chain containing 191 amino acid residues.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please see the lot-specific Certificate of Analysis.
Target Information
Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones that play an important role in growth control.
The GH1 gene, along with four additional related genes, is located at the growth hormone locus on chromosome 17. These genes share a high degree of sequence identity, and alternative splicing results in five isoforms ranging from approximately 19 kDa to 24 kDa.
HGH is produced by somatotroph cells in the pituitary and acts through binding to cytokine receptor subfamily membrane receptors.
Its major role in stimulating body growth is to induce the liver and other tissues to secrete IGF-1. It stimulates both differentiation and proliferation of myoblasts, as well as amino acid uptake and protein synthesis in muscle and other tissues.
Mutations or deletions in the gene lead to growth hormone deficiency and short stature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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