Thermo Fisher Scientific CDH20 Polyclonal Antibody
Human CDH20 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:20–1:50 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 저장용액에 40% 글리세롤 포함. 종 특이성은 Human이며, 연구용으로만 사용.
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Thermo Fisher Scientific CDH20 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CDH20. Recombinant protein control fragment (Product #RP-90036) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639590 |
Product Specific Information
Immunogen sequence:
PFQDTTTVHI SVEDVDEPPV FEPGFYFVEV PEDVAIGTTI QIISAKDPDV TNNSIRYSID RSSDPGRFFY VDITTGALMT ARPLDREEFS WHNITVLAME MNNPSQVGSV PVTIKV
Highest antigen sequence identity to the following orthologs:
- Mouse: 97%
- Rat: 97%
Target Information
This gene encodes a type II classical cadherin from the cadherin superfamily and is one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail.
Type II (atypical) cadherins are defined by their lack of a HAV cell adhesion recognition sequence specific to type I cadherins.
Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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