Thermo Fisher Scientific CDH20 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CDH20. Recombinant protein control fragment (Product #RP-90036). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CDH20,uniProtId:Q9HBT6-1,ncbiNodeId:9606,antigenRange:369-484,antigenLength:801,antigenImageFileName:PA5-53309_CDH20_Q9HBT6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53309_CDH20_Q9HBT6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639590

Product Specific Information

Immunogen sequence: PFQDTTTVHI SVEDVDEPPV FEPGFYFVEV PEDVAIGTTI QIISAKDPDV TNNSIRYSID RSSDPGRFFY VDITTGALMT ARPLDREEFS WHNITVLAME MNNPSQVGSV PVTIKV

Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

Target Information

This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.