Thermo Fisher Scientific B3GNT1 Polyclonal Antibody
Human B3GNT1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human B3GNT1. Recombinant protein control fragment (Product #RP-89938) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638421 |
Product Specific Information
Immunogen sequence:
EEQDQYFEFF PPSPRSVDQV KAQLRTALAS GGVLDASGDY RVYRGLLKTT MDPNDVILAT HASVDNLLHL SGLLERWEGP LSVSVFAATK EEAQLATVLA YALSSHCPDM RARVAMHLVC PSRYEAAVPD PREPGEFALL RSCQ
- Highest antigen sequence identity to orthologs:
- Mouse: 98%
- Rat: 97%
Target Information
Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1).
Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE during synthesis of phosphorylated O-mannosyl glycan.
Phosphorylated O-mannosyl glycan is a carbohydrate structure present in alpha-dystroglycan (DAG1), required for binding laminin G-like domain-containing extracellular proteins with high affinity.
Required for axon guidance via its function in O-mannosylation of alpha-dystroglycan (DAG1).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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