Thermo Fisher Scientific CCRL2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

Product Specifications

Product Specific Information

The antibody was affinity-purified from rabbit antiserum using an epitope-specific immunogen. Purity is greater than 95% as determined by SDS-PAGE.

Target Information

CCRL2 (C-C chemokine receptor-like 2), also known as chemokine receptor X, human chemokine receptor (HCR), CRAM-A, or CRAM-B, is a seven-pass transmembrane protein expressed by monocytes, neutrophils, and dendritic cells in immune tissues such as spleen, fetal liver, bone marrow, and lymph node.
It shares over 40% homology with other C-C chemokine receptors but lacks the conserved DRY motif, which is important for signaling and ligand-binding.
C-C chemokine receptors are G-protein coupled, seven-pass transmembrane domain proteins that function primarily in the chemotaxis of T cells and phagocytic cells to sites of inflammation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.