Thermo Fisher Scientific Contactin 2 Polyclonal Antibody
Rabbit polyclonal antibody against human Contactin 2 for Western blot applications. Affinity-purified with >95% purity. Supplied as liquid form, 1 mg/mL concentration. Suitable for neural development and axonal adhesion studies.
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- PA575496
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 157–202 of Human Contactin 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719224 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. Purity is >95% (by SDS-PAGE).
Target Information
Contactin 2 (CNTN2, transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1) is a neuronal cell adhesion molecule (CAM) that influences axon connection formation in the developing nervous system.
It is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol anchor, six Ig-like domains, and four Fibronectin type III (FNIII)-like domains.
Contactin 2 is expressed predominantly during neural development on axonal membranes to guide commissural axons without promoting growth.
It binds with NgCAM in cis-binding mode on the same membrane, and heterophilic binding sites (Contactin 2/NgCAM, Contactin 2/NrCAM) are localized to the first four Ig domains, while homophilic binding (Contactin 2/Contactin 2) occurs at the FNIII domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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