Thermo Fisher Scientific SENP5 Polyclonal Antibody
SENP5 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, IHC, ICC/IF에 적합합니다. 사람, 마우스, 영장류 시료에 반응하며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SENP5 (Accession Q96HI0), corresponding to amino acid residues F661–S711 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2853769 |
Product Specific Information
Antibody detects endogenous levels of total SENP5.
Target Information
SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions including transcription, DNA repair, nucleocytoplasmic trafficking, and chromosome segregation. SUMO precursor proteins undergo cleavage after the GG region by SUMO-specific proteases during maturation, which is essential for subsequent sumoylation.
Sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1–3 and SENP5–8. SENP1, SENP2, and SENP3 degrade UBL1 and SMT3H2 conjugates, releasing monomers from sumoylated substrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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