Thermo Fisher Scientific RHEB Monoclonal Antibody (GT39810)
RHEB 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot, IHC, ICC/IF에 적합. 인간, 생쥐, 랫드 등 다양한 종에 반응. 고순도 Protein A 정제, 1 mg/mL 농도, PBS 버퍼에 보존. 세포 성장 및 신호전달 연구용으로 최적화된 항체.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT39810 |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Rheb (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2735346 |
Product Specific Information
- Positive Control: SK-N-SH
- Predicted Reactivity:
Mouse (98%), Rat (99%), Zebrafish (90%), Xenopus laevis (91%), Pig (99%), Sheep (99%), Rhesus Monkey (100%), Bovine (98%) - Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Rheb encodes a member of the small GTPase superfamily and produces a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is essential for regulating growth and cell cycle progression via the insulin/TOR/S6K signaling pathway. It has GTPase activity and cycles between GDP-bound and GTP-bound forms; farnesylation is required for its function. Three pseudogenes have been mapped—two on chromosome 10 and one on chromosome 22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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