Thermo Fisher Scientific TRPM8 Polyclonal Antibody
TRPM8 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 사용 가능. 인간 시료에 반응하며, 합성 펩타이드를 면역원으로 제작. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용 가능.
- 카탈로그번호
- OST00209W-100UL
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous (PubMed) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the 1st cytoplasmic loop of human TRPM8 (TRPP8) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: TRPM8.
Target Information
TRPM8 is a receptor-activated non-selective cation channel involved in detection of cool sensations, being activated by cold temperatures below 25 °C. It is also activated by compounds such as icilin, eucalyptol, and menthol, as well as by intracellular pH modulation.
TRPM8 is permeable to monovalent cations (Na⁺, K⁺, Cs⁺) and divalent calcium ions (Ca²⁺). Expression is mainly in prostate epithelial cells, with moderate levels in normal prostate tissue and elevated levels in prostate cancer. TRPM8 mRNA is also expressed in several non-prostatic tumors (breast, colon, lung, skin), but rarely in corresponding normal tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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