Thermo Fisher Scientific PAR2 Polyclonal Antibody
PAR2 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응합니다. IHC(P)에서 3 µg/mL로 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 1 mg/mL 농도로 PBS에 0.1% sodium azide를 포함합니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from N-terminal extracellular domain of human F2RL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550906 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla (100%)
- Gibbon, Marmoset (95%)
- Monkey (90%)
- Panda (80%)
Target Information
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also part of the protease-activated receptor family and is activated by trypsin but not thrombin. Activation occurs through proteolytic cleavage of its extracellular amino terminus, generating a tethered ligand that activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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