Thermo Fisher Scientific PAR2 Polyclonal Antibody
Human F2RL1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ELISA에서 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 10 µg/mL | - |
| ELISA | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from 2nd extracellular domain of human F2RL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550907 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gibbon, Monkey (100%)
Marmoset, Mouse, Rat, Hamster (94%)
Gorilla, Horse, Pig (89%)
Target Information
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins.
F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin, through proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor.
The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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