Thermo Fisher Scientific TYMP Monoclonal Antibody (OTI7A6), TrueMAB
TYMP 단백질을 인식하는 마우스 모노클로날 항체로, Western blot과 IHC(P) 실험에 적합합니다. 인간 시료 반응성이 있으며, 액상 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제, 안정적인 PBS/BSA/glycerol 버퍼 구성.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7A6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 311–482 of human TYMP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
A platelet-derived endothelial growth factor (PD-ECGF), also known as thymidine phosphorylase (TP) or gliostatin.
In the presence of inorganic orthophosphate, it catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate.
It is both chemotactic and mitogenic for endothelial cells and acts as a non-heparin binding angiogenic factor present in platelets.
Additionally, it is involved in the transformation of fluoropyrimidines—cytotoxic agents used in cancer treatment—into active cytotoxic metabolites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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