Thermo Fisher Scientific TUBB5/Beta V Tubulin Polyclonal Antibody
TUBB5/Beta V Tubulin 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, WB, IHC, ICC, ELISA 등에 사용 가능. 고순도 Protein A 정제, 1 mg/mL 농도, 다양한 종(Human, Mouse, Rat, Xenopus)에 반응. 연구용으로 안정적인 결합 특성 제공.
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Thermo Fisher Scientific TUBB5/Beta V Tubulin Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat, Xenopus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human TUBB5/Beta V Tubulin (amino acids 301–444) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA and 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Microtubules are major cytoskeletal elements found in all eukaryotic cells, composed of tubulin dimers (alpha and beta subunits, ~55 kDa each). They play essential roles in:
- Chromosome segregation during mitosis
- Intracellular transport
- Ciliary and flagellar movement
- Structural support of the cytoskeleton
This antibody does not induce collapse of 10-nm filaments or block microtubule assembly. It does not inhibit polymerization or depolymerization of platelet tubulin in vitro but blocks 70–80% of the ability of tubulin dimers (with GppNHp bound) to promote stable inhibition of adenylyl cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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