Thermo Fisher Scientific Gram Negative Endotoxin Monoclonal Antibody (GNE13-305.6)

Applications

Tested Dilution

Publications

ELISA (ELISA)

1-10 µg/mL

-

Product Specifications

Species Reactivity

Bacteria

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

GNE13-305.6

Immunogen

E. coli serotypes: O:111, B4 J5.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.8 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1074796

Product Specific Information

MA1-10685 detects Endotoxin from E. coli, Sh. sonnei, and S. typhimurium samples.

MA1-10685 has been successfully used in ELISA applications.

The MA1-10685 immunogen is E. coli serotypes: O:111, B4 J5.

Target Information

Endotoxins are part of the outer membrane of the cell wall of gram-negative bacteria. Endotoxins are invariably associated with gram-negative bacteria whether the organisms are pathogens or not. Although the term endotoxin is occasionally used to refer to any cell-associated bacterial toxin, it is properly reserved to refer to the lipopolysaccharide complex associated with the outer membrane of gram-negative bacteria such as E. coli, Salmonella, Shigella, Pseudomonas, Neisseria, Haemophilus, and other leading pathogens. The biological activity of endotoxin is associated with the lipopolysaccharide (LPS). Toxicity is associated with the lipid component (Lipid A) and immunogenicity is associated with the polysaccharide components. The cell wall antigens (O antigens) of gram-negative bacteria are components of LPS. LPS elicits a variety of inflammatory responses in an animal. Because it activates complement by the alternative (properdin) pathway, it is often part of the pathology of gram-negative bacterial infections.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.