Thermo Fisher Scientific RPS10 Polyclonal Antibody
RPS10 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC/IF에 적합. Human 및 Mouse 반응성 검증됨. 항원 친화 크로마토그래피로 정제된 액상 시약. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to amino acids 1–151 (UniProt ID: P46783) of RPS10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.57 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11155585 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain
- Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (90%), Xenopus laevis (96%), Dog (100%), Pig (99%), Chicken (98%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Ribosomes are organelles responsible for protein synthesis, composed of a small subunit (40S) and a large subunit (60S) containing over 80 distinct ribosomal proteins.
Ribosomal Protein S10 (RPS10) is a 165-amino-acid component of the 40S subunit. It is typically cytoplasmic but can localize to the granular component (GC) region of the nucleolus when methylated by PRMT5 and interacting with NPS1.
Defects in RPS10 cause Diamond-Blackfan anemia type 9 (DBA9), a congenital hypoplastic anemia characterized by macrocytic anemia, erythroblastopenia, and increased malignancy risk.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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