Thermo Fisher Scientific Phospho-MEF2D (Ser444) Polyclonal Antibody
MEF2D 단백질의 Ser444 인산화 부위를 인식하는 토끼 폴리클로날 항체. Western blot 및 파라핀 조직 면역조직화학에 적합. 액상 형태로 1 mg/mL 농도 제공. 근육 및 신경 분화 연구용으로 적합하며, 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human MEF2D around the phosphorylation site of Ser444 (P‑V‑SP‑P‑S) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | −20 °C |
| Shipping conditions | Wet ice |
| RRID | AB_2554894 |
Target Information
The MEF2D gene belongs to the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. These proteins regulate muscle and neuronal cell differentiation and development, and are modulated by class II histone deacetylases. Fusions with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) have been observed in acute lymphoblastic leukemia cell lines, suggesting a potential role in leukemogenesis. The encoded protein may also be implicated in Parkinson’s disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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