Thermo Fisher Scientific GLP-1 Monoclonal Antibody (4)

Applications

Tested Dilution

Publications

Western Blot (WB)

-

View 1 publication 1 publication

Immunohistochemistry (IHC)

1:500

-

Immunocytochemistry (ICC/IF)

-

View 1 publication 1 publication

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

4

Immunogen

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View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.02 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

15mM sodium azide

Storage conditions

4° C, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1074636

Product Specific Information

ABS 033-04-02 detects the amidated N-terminus of GLP-1(7-37) and GLP-1(7-36) in human samples.

ABS 033-04-02 has been successfully used in ELISA procedures. ABS 033-04-02 binds the free N-terminus of GLP-1(7-37) and GLP-1(7-36) amide and shows < 0.2% cross-reactivity with GLP-1(1-37), GLP-1(9-36) amide, glucagon, human GIP and exendin-4. ABS 033-04-02 cross-reacts approximately 1% with human GLP-2. Not recommended for sandwich ELISA applications.

NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL

Target Information

GCG is also known as GLP1, or Glucagon. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis.It is mapped to 2q36-2q37. GLP1, also known as 7-37 for the codons of the preproglucagon molecule which encode it, renders pancreatic beta-cells glucose-competent and may be useful in the treatment of noninsulin-dependent diabetes mellitus. Also, GLP1 is a potent insulin secretagogue.It plays a major role in the enteroinsular axis, accounting, for example, for the finding that plasma insulin levels accompanying oral intake of glucose are greater than those observed when glucose is given intravenously.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.