Thermo Fisher Scientific Bovine Transferrin Polyclonal Antibody
소, 락토페린 단백질을 인식하는 Thermo Fisher의 폴리클로날 항체로서 WB, IHC, ICC, ELISA 등에 사용 가능. Sheep IgG 기반, 비결합형 액상 형태이며 항원 친화 크로마토그래피로 정제됨. 철 결합 및 면역 방어 연구용으로 적합.
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Thermo Fisher Scientific Bovine Transferrin Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 – 1:30,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 – 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200 – 1:2,000 |
| ELISA | 1:1,000 – 1:30,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Bovine |
| Host/Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 6.8–7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Lactoferrin (LF) is an iron-binding glycoprotein consisting of a single polypeptide chain (~80 kDa) folded into two homologous lobes, each capable of reversibly binding one ferric ion (Fe³⁺). LF is found in milk and mucosal secretions and is a major component of neutrophil secondary granules. It plays roles in iron homeostasis regulation, host defense against microbial infections, anti-inflammatory activity, cellular growth and differentiation regulation, and protection against cancer development and metastasis.
LTF acts as a first-line defense against microbial infections by binding and removing Fe³⁺ from the environment and exhibits bactericidal and proteolytic activities. Three isoforms (LTF-α, LTF-β, LTF-γ) have been identified, and receptors for LTF are expressed in the gastrointestinal tract, macrophages, lymphocytes, neutrophils, platelets, and some bacteria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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