Thermo Fisher Scientific Bovine Transferrin Polyclonal Antibody, HRP
소, 락토페린 단백질을 인식하는 HRP 결합 폴리클로날 항체. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 감도를 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Bovine Transferrin Polyclonal Antibody, HRP
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 – 1:30,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 – 1:500 |
| Immunocytochemistry (ICC/IF) | 1:200 – 1:500 |
| ELISA | 1:10,000 – 1:100,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine |
| Host/Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Conjugate | HRP |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 6.8–7.4 |
| Contains | 0.05% Pro-Clean 400 |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Target Information
Lactoferrin (LF) is an iron-binding glycoprotein composed of a single polypeptide chain (~80 kDa) folded into two homologous lobes, each capable of reversibly binding one ferric ion (Fe³⁺). LF is present in external fluids such as milk and mucosal secretions and forms a major component of neutrophil secondary granules.
It exhibits diverse biological functions including:
- Regulation of iron homeostasis
- Host defense against microbial infections
- Anti-inflammatory activity
- Control of cellular growth and differentiation
- Protection against cancer development and metastasis
LTF acts as a first-line defense against microbes by binding and removing Fe³⁺ from the environment. It also shows bactericidal and proteolytic activities, cleaving arginine-rich sequences in microbial proteins. Three isoforms (LTF-α, LTF-β, LTF-γ) have been identified, and LTF receptors are expressed in the gastrointestinal tract, macrophages, lymphocytes, neutrophils, platelets, and certain bacteria.
Additional Information
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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