Thermo Fisher Scientific ANP32C Polyclonal Antibody
ANP32C 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성을 가지며, Protein A로 정제된 1 mg/mL 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ANP32C (amino acids 81–180) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ANP32C (acidic leucine-rich nuclear phosphoprotein 32 family, member C), also known as PP32R1 or tumorigenic protein pp32r1, is a 234 amino acid protein containing four leucine-rich repeats and belongs to the ANP32 family.
ANP32C shares 87.7% amino acid sequence identity with ANP32A, a tumor suppressor involved in various cancers such as prostate and breast cancer.
Unlike ANP32A, ANP32C is tumorigenic and expressed in activated stem cells (mobilized and cord blood CD34+ cells) but not in resting bone marrow CD34+ cells.
It is also expressed in neoplastic cell lines, particularly prostatic adenocarcinoma, and may modulate the oncogenic potential of human prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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