Thermo Fisher Scientific Hair Cortex Cytokeratin Monoclonal Antibody (AE13)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (IHC)

-

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent

-

Flow Cytometry (Flow)

1:20-1:50

-

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

AE13

Immunogen

Human hair keratins from P3X63Ag. 8.653 cells if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Hair Cortex Cytokeratin,uniProtId:Q6A162-1,ncbiNodeId:9606,antigenRange:1-431,antigenLength:431,antigenImageFileName:MA1-5765_Hair_Cortex_Cytokeratin_Q6A162-1_House_mouse.svg,antigenImageFileNamePDP:MA1-5765_Hair_Cortex_Cytokeratin_Q6A162-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.2

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1075198

Product Specific Information

MA1-5765 detects Cytokeratin, AE13 in human and mouse samples.

MA1-5765 has been successfully used in Western blot, immunocytochemistry, immunofluorescence and immunohistochemistry procedures.

The MA1-5765 immunogen is human hair keratins.

This antibody reacts with acidic 44-46 kDa hair cortex keratins.

Target Information

Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratin 5, 6 and 8 are members of the type II neutral-to-basic subfamily. Monoclonal antibodies to cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. PCK-26 facilitates the typing of normal, metaplastic and neoplastic cells and it may aid in the discrimination of carcinomas and non-epithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micro-metastases in lymph nodes and other tissues and for determining the origin of poorly differentiated tumors (1,2).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.