Thermo Fisher Scientific Hair Cortex Cytokeratin Monoclonal Antibody (AE13)
인간 및 생쥐 시료에서 모발 피질 사이토케라틴을 검출하는 단클론 항체. Western blot, IHC, Flow cytometry 등 다양한 응용에 적합. 단백질 G 정제, 액상 형태로 제공되며 4°C 또는 -20°C에서 안정적 보관 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | - | View 6 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| Flow Cytometry (Flow) | 1:20–1:50 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AE13 |
| Immunogen | Human hair keratins from P3X63Ag.8.653 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1075198 |
Product Specific Information
MA1-5765 detects Cytokeratin AE13 in human and mouse samples.
It has been successfully used in Western blot, immunocytochemistry, immunofluorescence, and immunohistochemistry procedures.
The immunogen is human hair keratins.
This antibody reacts with acidic 44–46 kDa hair cortex keratins.
Target Information
Cytokeratins are a group comprising at least 29 different proteins characteristic of epithelial and trichocytic cells.
Cytokeratin 5, 6, and 8 belong to the type II neutral-to-basic subfamily.
Monoclonal antibodies to cytokeratins serve as specific markers of epithelial cell differentiation and are widely used for tumor identification and classification.
They facilitate the typing of normal, metaplastic, and neoplastic cells and aid in distinguishing carcinomas from non-epithelial tumors such as sarcomas, lymphomas, and neural tumors.
They are also useful for detecting micro-metastases in lymph nodes and other tissues and determining the origin of poorly differentiated tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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