Thermo Fisher Scientific GNPDA2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GNPDA2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GNPDA2,uniProtId:Q8TDQ7-1,ncbiNodeId:9606,antigenRange:178-244,antigenLength:276,antigenImageFileName:PA5-61366_GNPDA2_Q8TDQ7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61366_GNPDA2_Q8TDQ7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642097

Product Specific Information

Immunogen sequence: LSKVPTMALT VGVGTVMDAR EVMILITGAH KAFALYKAIE EGVNHMWTVS AFQQHPRTIF VCDEDAT

Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 100%.

Target Information

GNPDA2 (Glucosamine-6-phosphate deaminase) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. GNPDA2 is the second mammalian glucosamine-6-phosphate deaminase discovered, and is closer in structure and activity to the E. coli enzyme than GNPDA1. GNPDA1 possesses greater affinity for ammonium than either GNPDA2 or the E. coli enzyme suggesting that the forward reaction of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium is catalyzed at a slower rate than GNPDA2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.