Thermo Fisher Scientific ACADM Polyclonal Antibody, Biotin
ACADM 단백질을 인식하는 Biotin 결합 산양 다클론 항체로, Western blot 및 IHC에 적합합니다. 인간 시료 반응성이 있으며, 고순도 액상 형태로 제공됩니다. TBS 버퍼(0.5% BSA 포함)에서 안정화되어 있으며, 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–4 µg/mL |
| Immunohistochemistry (IHC) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-RLIVAREHIDKYKN (aa 408–421) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932682 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms (NP_000007.1; NP_001120800.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
The ACADM gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase.
This homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway.
Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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