Thermo Fisher Scientific SOCS5 Polyclonal Antibody

Applications

• Western Blot (WB): 0.3–1 µg/mL

Product Specifications

Product Specific Information

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.

Target Information

Cytokine receptor signaling is negatively regulated by the SOCS (Suppressor of Cytokine Signaling) family, which includes SOCS-1 through SOCS-7 and CIS. These proteins contain an N-terminal variable region, a central SH2 domain, and a C-terminal SOCS box. They form part of a negative feedback loop that modulates cytokine signal transduction through STAT-induced transcriptional mechanisms. SOCS gene transcription is rapidly induced by cytokines, and each member inhibits signaling in distinct ways.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.