Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1 Recombinant Rabbit Monoclonal Antibody (3E7H5)
SARS-CoV-2 Spike Protein S1을 인식하는 재조합 토끼 단클론 항체. WB, ICC/IF, ELISA에 적합. HEK293 세포에서 발현된 IgG 형태로, 고순도의 Affinity chromatography 정제. 연구용으로만 사용 가능.
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Applications 및 권장 희석 배율
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3E7H5 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 200–300 of SARS-CoV-2 Spike S1 (YP_009724390.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.28 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3090467 |
Product Specific Information
Immunogen sequence:
YFKIYSKHTP INLVRDLPQG FSALEPLVDL PIGINITRFQ TLLALHRSYL TPGDSSSGWT AGAAAYYVGY LQPRTFLLKY NENGTITDAV DCALDPLSET K
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, is a virus that causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death.
The Spike protein consists of S1 and S2 domains and serves as the main surface antigen of the coronavirus.
The glycosylated Spike protein and nucleocapsid protein can be detected in infected cell culture supernatants using antisera from SARS patients.
The S1 domain contains a receptor-binding domain (RBD) that binds specifically to ACE2 receptors on target cells.
Variations in Spike proteins reflect CoV diversity and influence receptor interactions and fusion responses.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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