
Thermo Fisher Scientific xCT/SLC7A11 (extracellular) Polyclonal Antibody
xCT/SLC7A11 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot, IHC(F), Flow Cytometry에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:300 |
| Flow Cytometry (Flow) | 2.5 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)THHFKDAFSGRDTS, corresponding to amino acid residues 218–231 of mouse cystine/glutamate transporter, 3rd extracellular loop |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size
- Ships as lyophilized powder at room temperature
- Upon arrival, store at -20°C
- Reconstituted solution can be stored at 4°C for up to 1 week
- For longer storage, aliquot and store at -20°C
- Avoid multiple freeze/thaw cycles
- Centrifuge all antibody preparations before use (10,000 × g, 5 min)
Target Information
SLC7A11 (also known as xCT) is a member of a heteromeric, sodium-independent anionic amino acid transport system. It is highly specific for cysteine and glutamate. SLC7A11 mediates Kaposi sarcoma-associated herpesvirus fusion and cell entry. Increased expression in primary gliomas is associated with neuronal cell death.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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