Thermo Fisher Scientific Kir4.1 (KCNJ10) Polyclonal Antibody
Kir4.1(KCNJ10) 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. WB에 1:500–1:1,000 희석 비율로 사용 가능하며, 항원 친화 크로마토그래피로 정제된 고순도 제품입니다. 신경계 연구 및 칼륨 채널 관련 연구용으로 적합합니다.
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Thermo Fisher Scientific Kir4.1 (KCNJ10) Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in human KIR4.1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553926 |
Product Specific Information
- Detects endogenous protein at a molecular weight of 42 kDa.
- Purity is >95% by SDS-PAGE.
Target Information
The KIR (inwardly rectifying potassium channel) family allows potassium ions to flow more readily into cells than out of them.
KIR4.1 (also known as Kir1.2) is highly expressed in the brain, including glial cells, astrocytes, and cortical neurons. It is also found in myelin-synthesizing oligodendrocytes and plays a crucial role in myelination during nervous system development.
The human KIR4.1 gene maps to chromosome 1.
KIR4.2 (Kir1.3) is expressed in kidney, lung, heart, thymus, and thyroid during development, and its gene maps to chromosome 21 in the Down syndrome region—potentially implicating it in Down syndrome pathogenesis.
KIR5.1 forms functional channels only when coexpressed with KIR4.1 or KIR4.2 in kidney and pancreas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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