Thermo Fisher Scientific Embigin Polyclonal Antibody
Human Embigin 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 5–7.5 µg/mL로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상형 항체이며, PBS buffer 및 sodium azide 포함. 세포 부착 및 발달 관련 연구용으로 적합.
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- PA532745
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- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 5–7.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from C-terminus of human EMB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550207 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon (100%), Monkey (94%), Marmoset, Elephant (88%), Dog, Rabbit (82%).
Target Information
Embigin is a 327 amino acid regulatory protein belonging to the immunoglobulin superfamily class of CAMs, possessing two Ig-like V-type domains. In situ hybridization analysis shows that Embigin has specific carbohydrate epitopes and plays an important role in early postimplantation embryogenesis.
A highly glycosylated transmembrane glycoprotein, Embigin regulates cell/ECM interactions during development and homeostasis of normal tissues. Transfection studies suggest its role in promoting integrin-mediated cell-substratum adhesion.
Widely expressed in most tissues and embryonal carcinoma cells, prostate and mammary cancer cell lines, it may assist in classification of human carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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