Thermo Fisher Scientific FGD1 Polyclonal Antibody
FGD1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 4°C에서 보관, 연구용으로만 사용 가능.
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- A305214Ax (2개 옵션)
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Thermo Fisher Scientific FGD1 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): Assay-dependent
- Immunoprecipitation (IP): 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 50 to 100 of human FYVE, RhoGEF and PH domain-containing protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It binds specifically to the Rho family GTPase Cdc42Hs and stimulates GDP-GTP exchange of its isoprenylated form. FGD1 also activates the MAPK cascade, leading to c-Jun kinase (SAPK/JNK1) activation.
FGD1 plays an essential role in embryonic development, and mutations in the FGD1 gene cause the human developmental disorder Aarskog-Scott syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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