Thermo Fisher Scientific HK2 Monoclonal Antibody (H.738.7)
HK2 단클론 항체(H.738.7)는 인간 및 생쥐 시료에서 Hexokinase II 단백질 검출용으로 사용됩니다. Western blot 및 IHC에 적합하며, 비결합 액상 형태로 제공됩니다. 연구용으로만 사용 가능하며, 안정적인 성능과 높은 특이성을 제공합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- View 1 publication
Immunohistochemistry (IHC)
- Tested Dilution: –
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | H.738.7 |
| Immunogen | Synthetic peptide corresponding to residues surrounding Ser340 of sequence of human hexokinase II |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 24 µg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_10987229 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV.
Hexokinase activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway.
Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P.
Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.
Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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