Thermo Fisher Scientific PHLDA2 Polyclonal Antibody
PHLDA2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 검증됨. 인체 시료 반응성, 액상 형태, Affinity chromatography로 정제. 세포 성장 조절 및 발달 관련 연구에 적합. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PHLDA2 (Accession Q53GA4), corresponding to amino acid residues E87–P137 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818225 |
Product Specific Information
This antibody detects endogenous levels of total PHLDA2.
Target Information
TSSC3 (Tumor-suppressing STF cDNA 3 protein), also known as PHLDA2 (pleckstrin homology-like domain family A member 2), BWR1C, HLDA2, or IPL, is a cytoplasmic protein involved in fetal and placental growth. It is highly expressed in placenta and adult prostate, and at lower levels in liver, lung, and brain. TSSC3 functions as an apoptosis-related protein and negative growth regulator expressed during normal human development. The gene is maternally imprinted and expressed during embryogenesis, with expression ceasing after development. Mutations or alterations in TSSC3 are associated with diseases such as lung, ovarian, and breast cancer, rhabdomyosarcoma, Beckwith-Wiedemann syndrome, Wilms tumor, low birth weight, and adrenocortical carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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