Thermo Fisher Scientific ACSS2 Polyclonal Antibody
Human ACSS2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot, IHC, ICC/IF 등에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태이며, PBS 버퍼와 글리세롤 포함. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | – |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ACSS2. Recombinant protein control fragment (Product #RP-102332). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637634 |
Product Specific Information
Immunogen sequence:
PGETTQITYH QLLVQVCQFS NVLRKQGIQK GDRVAIYMPM IPELVVAMLA CARIGALHSI VFAGFSSESL CERILDSSCS LLITTDAFYR GEKLVNLKEL ADEALQKCQE KGFPVRCCIV VKHLGRAELG MGDSTSQSPP IKRSCPDVQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 91%
- Rat: 90%
Target Information
This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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