Thermo Fisher Scientific MEK1/2 Polyclonal Antibody
MEK1/2 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간, 마우스, 랫트에 반응. Western blot 및 IHC(P) 등에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 제품으로 안정화 PBS 버퍼 포함. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide surrounding the epitope -SMANS- without phosphorylation of human MEK1/2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Human kidney
- Cellular location: Cytoplasm
Target Information
MEK1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003).
In brain, this pathway also plays a key role in synaptic signaling (Adams and Sweatt, 2002).
Activated MEK1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: 620-180_MEK12_P36507-1_Rabbit.svg, 620-180_MEK12_P36507-1_Rabbit_PDP.jpeg)
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