
Thermo Fisher Scientific TIA1 (T-Cell-Restricted Intracellular Antigen-1) Monoclonal Antibody (TIA1/1313)
TIA1 단백질을 인식하는 Mouse monoclonal antibody로, Western blot, ICC/IF, Flow cytometry에 적합합니다. Human 시료에 반응하며 Protein A로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific TIA1 (T-Cell-Restricted Intracellular Antigen-1) Monoclonal Antibody (TIA1/1313)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 0.5–1 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TIA1/1313 |
| Immunogen | Recombinant human TIA1 fragment of 102 amino acid residues (aa279–380) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through signals from WNT3A to stabilize beta-catenin and Noggin, which acts as a bone morphogenetic protein inhibitor. Mutations in Noggin are associated with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1), characterized by multiple joint fusion defects.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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