
Thermo Fisher Scientific TIA1 (T-Cell-Restricted Intracellular Antigen-1) Monoclonal Antibody (rTIA1/1353)
TIA1 단백질을 인식하는 Mouse monoclonal antibody로, 인간 시료에 반응합니다. IHC(PFA 고정) 실험에 적합하며, Protein A로 정제된 액상 형태입니다. 보존제가 없으며, -20°C에서 보관합니다.
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Applications
- Immunohistochemistry (PFA fixed) (IHC (PFA)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rTIA1/1353 |
| Immunogen | Recombinant full-length human TIA1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through signals from:
- WNT protein (WNT3A) to stabilize beta-catenin
- Noggin, a bone morphogenetic protein inhibitor
Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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