Thermo Fisher Scientific CA125 Monoclonal Antibody (X325)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

X325

Immunogen

CA125 antigen purified from human ovarian carcinoma. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CA125,uniProtId:Q8WXI7-1,ncbiNodeId:9606,antigenRange:1-14507,antigenLength:14507,antigenImageFileName:MA1-74328_CA125_Q8WXI7-1_House_mouse.svg,antigenImageFileNamePDP:MA1-74328_CA125_Q8WXI7-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Ion-exchange chromatography

Storage buffer

PBS

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_1954952

Product Specific Information

MA1-74328 recognizes the epitope specificity group B, similar to the M-11 antibody.

A suggested positive control for immunohistochemical applications is lung adenocarcinoma, serosal ovarian adenocarcinoma or urinary bladder adenocarcinoma tissue.

Target Information

CA 125 determinant is present on a high molecular weight, mucin like glycoprotein of high molecular weight. CA 125 has been found on frozen sections of amnion and derivatives of coelomic and mullerian epithelium, including pleura, pericardium and peritoneum. In adult tissues, epithelial cells of fallopian tube, endometrium and endocervix; pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland and mammary gland. It is also found in mesothelial cell lining of pleura, pericardium and peritoneum. It is found in ovarian tumors of serous, endometrioid or clear cell types and adenocarcinomas of mullerian type.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.