ELK Biotechnology Ephrin-A2 rabbit pAb
Ephrin-A2 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 사용 가능. 인간과 생쥐 시료에 반응하며, 세포막 GPI-앵커 단백질 검출에 적합. 고순도 IgG, 1 mg/ml 농도. -20°C에서 1년 보관 가능.
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제품명
Ephrin-A2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | EFNA2; EPLG6; LERK6; Ephrin-A2; EPH-related receptor tyrosine kinase ligand 6; LERK-6; HEK7 ligand; HEK7-L |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human EFNA2. AA range: 1-50 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 24 kD |
| Gene ID (Human) | 1943 |
| Human Swiss-Prot No. | O43921 |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system.
Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins.
Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm.
[provided by RefSeq, Jul 2008]
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