ELK Biotechnology DGK-ι rabbit pAb
DGK-ι rabbit pAb는 인간 DGKI 유래 펩타이드로부터 제작된 다클론 항체로, WB, IHC, IF, ELISA에 적합합니다. 세포 내 시냅스 및 핵에서 발현되는 DGKI 단백질 검출에 유용하며, 고순도 IgG 형태로 안정적 장기 보관이 가능합니다.
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제품명
DGK-ι rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | DGKI; Diacylglycerol kinase iota; DAG kinase iota; Diglyceride kinase iota; DGK-iota |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human DGKI (AA range: 991–1040) |
| Species Reactivity | Human; Rat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 160 kD |
| GeneID (Human) | 9162 |
| Human Swiss-Prot No | O75912 |
| Storage | -20°C / 1 year |
| Host Species | Rabbit |
세포 내 위치 (Cellular Localization)
Cell projection (axon, dendrite), cell junction (synapse, presynapse, postsynapse, postsynaptic density), synaptic cell membrane, cytoplasmic vesicle (secretory, synaptic vesicle membrane), cytoplasm (cytosol), nucleus.
Excluded from inhibitory synapses (By similarity). Localization between cytoplasm and nucleus is regulated by protein kinase C (PubMed:9830018). Present in both detergent-soluble and particulate fractions (By similarity).
배경 (Background)
This gene belongs to the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate intracellular diacylglycerol concentration through phosphorylation to produce phosphatidic acid. Although the specific role of this enzyme is not fully determined, it may be crucial for phosphatidic acid production in the retina or in recessive forms of retinal degeneration.
[Provided by RefSeq, Jul 2008]
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