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ELK Biotechnology DR4 rabbit pAb
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ELK Biotechnology DR4 rabbit pAb

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Human TNFRSF10A 단백질을 인식하는 DR4 rabbit polyclonal antibody. Western blot, IF, ELISA에 적합하며, 세포막 및 세포질에 위치한 DR4 단백질 검출에 사용. 고순도 IgG, 농도 1 mg/ml, -20°C에서 1년 보관 가능.

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pk
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ELK Biotechnology ES2198-100UL DR4 rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES2198-50UL DR4 rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology DR4 rabbit pAb

제품명

DR4 rabbit pAb

제품 개요

이 항체는 인간 TNFRSF10A(Death Receptor 4, DR4)를 인식하는 rabbit polyclonal antibody입니다. TRAIL에 의해 활성화되는 세포사멸 경로 연구에 유용합니다.

주요 정보

항목 내용
Product name DR4 rabbit pAb
Alternative Names TNFRSF10A; APO2; DR4; TRAILR1; Tumor necrosis factor receptor superfamily member 10A; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; CD antigen CD261
Applications WB; IF; ELISA
Recommended Dilutions Western Blot: 1/500 - 1/2000
Immunofluorescence: 1/200 - 1/1000
ELISA: 1/5000
Not yet tested in other applications
Immunogen The antiserum was produced against synthesized peptide derived from human TNFRSF10A (AA range: 401-450)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 50 kD
Gene ID (Human) 8797
Human Swiss-Prot No O00220
Cellular Localization Cell membrane; Single-pass type I membrane protein; Membrane raft; Cytoplasm, cytosol. Palmitoylation is required for membrane association.
Species Reactivity Human; Monkey

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis-inducing ligand (TNFSF10/TRAIL), and transduces cell death signals to induce apoptosis. Studies using FADD-deficient mice suggest that FADD, a death domain-containing adaptor protein, is required for apoptosis mediated by this receptor.
[Provided by RefSeq, Jul 2008]

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