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ELK Biotechnology Cox-2 rabbit pAb
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Cox-2 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 랫드, 마우스 반응성. 염증 및 세포 증식 관련 연구에 적합하며, -20°C에서 1년 보관 가능.
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ELK Biotechnology ES2034-100UL Cox-2 rabbit pAb, 100UL pk판매 단위 pk ·
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ELK Biotechnology ES2034-50UL Cox-2 rabbit pAb, 50UL pk판매 단위 pk ·
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ELK Biotechnology · ELK Biotechnology Cox-2 rabbit pAb
제품명
Cox-2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | PTGS2; COX2; Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/20000 Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cox2. AA range: 555-604 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 70 kD |
| Gene ID (Human) | 5743 |
| Human Swiss-Prot No | P35354 |
| Cellular Localization | Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus inner membrane; Peripheral membrane protein. Nucleus outer membrane; Peripheral membrane protein. Detected on the lumenal side of the endoplasmic reticulum and nuclear envelope. |
| Species Reactivity | Human; Rat; Mouse |
Background
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
[provided by RefSeq, Feb 2009]
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