ELK Biotechnology COL5A3 rabbit pAb
COL5A3 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 랫, 마우스 시료 반응성. 합성 펩타이드 유래 항원으로 제작되었으며, -20°C에서 1년 보관 가능.
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제품명
COL5A3 rabbit pAb
제품 개요
COL5A3 (Collagen alpha-3(V) chain)을 인식하는 토끼 폴리클로날 항체입니다.
Type V collagen은 Type I collagen과 함께 조직 내에서 발견되며, 섬유 조립을 조절하는 역할을 합니다.
이 항체는 인간, 랫, 마우스 시료에서 반응성을 보입니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | COL5A3 rabbit pAb |
| Alternative Names | COL5A3; Collagen alpha-3(V) chain |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Collagen V alpha3 (AA range: 221–270) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 170 kDa |
| Gene ID (Human) | 50509 |
| Human Swiss-Prot No. | P25940 |
| Cellular Localization | Secreted, extracellular space, extracellular matrix |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes an alpha chain for one of the low abundance fibrillar collagens.
Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains.
Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen.
This gene product is closely related to type XI collagen, and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations.
Mutations in this gene are thought to be responsible for symptoms of a subset of patients with Ehlers-Danlos syndrome type III.
Messages of several sizes can be detected in northern blots, but sequence information cannot confirm the identity of the shorter messages.
[Provided by RefSeq, Jul 2008]
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